ABSTRACT
BACKGROUND: Candida Parapsilosis is an unusual agent of prosthetic endocarditis in immunocompetent individuals but Coronavirus disease 2019 is reported to be associated with a transient immunodeficency that exposes patientes to opportunistic infections. CASE REPORT: We describe a dreadful case of Candida Parapsilosis endocarditis in a transient immunosuppressed patient recently infected with severe acute respiratory syndrome-Coronavirus 2019. CONCLUSION: Considering that the symptoms of Candida Parapsilosis infection and the symptoms of Coronavirus disease-2019 may overlap, it is important never to understimate the non-specific symptoms to improve patient outcome, especially in patient with previous Coronavirurs disease-2019 infection and with prosthetic material grafting.
Subject(s)
Abscess , COVID-19 , Candida parapsilosis , Candidiasis , Endocarditis , Heart Valve Prosthesis , Abscess/etiology , Abscess/microbiology , Abscess/surgery , COVID-19/complications , COVID-19/immunology , Candida parapsilosis/isolation & purification , Candidiasis/etiology , Candidiasis/microbiology , Endocarditis/etiology , Endocarditis/microbiology , Endocarditis/surgery , Heart Valve Prosthesis/adverse effects , Heart Valve Prosthesis/microbiology , Humans , Immunocompromised Host , Reoperation , Risk Factors , SARS-CoV-2ABSTRACT
A 42-year-old man was referred to the Department of Orthopedic Surgery with pain over his right greater trochanter and signs of systemic infection. CT showed an enhanced mass in his gluteus maximus as well as gas in the biceps femoris over the underlying hip joint. Tissue biopsy yielded Fusobacterium nucleatum and Actinomyces turicensis. The patient was successfully treated for 6 weeks with amoxicillin/clavulanic acid 875mg/125mg and metronidazole 500mg.
Subject(s)
Actinomycetaceae/isolation & purification , Actinomycetales Infections/microbiology , Bacteremia/microbiology , COVID-19/immunology , Fusobacterium Infections/microbiology , Fusobacterium nucleatum/isolation & purification , Hip/microbiology , Abscess/drug therapy , Abscess/microbiology , Actinomycetaceae/drug effects , Actinomycetaceae/genetics , Actinomycetales Infections/drug therapy , Adult , Anti-Bacterial Agents/therapeutic use , COVID-19/virology , Fusobacterium Infections/drug therapy , Fusobacterium nucleatum/drug effects , Fusobacterium nucleatum/genetics , Humans , Immunocompromised Host , Male , SARS-CoV-2/genetics , SARS-CoV-2/isolation & purificationABSTRACT
The world has suffered over the past year under COVID-19. Unfortunately, people still are getting sick from other, also severe, diseases. Although the COVID-19 infection is present, patients need treatment for other life-threatening conditions. We present the case of a 36-year-old patient with severe infective endocarditis with a large abscess of the aortic root, who also is COVID-19 positive. Definitive diagnostics and treatment were avoided due to COVID-19 infection. In the end, emergent surgery was indicated due to acute cardiac decompensation and the development of heart failure symptoms, and the patient recovered uneventfully after surgery.